Sievers 500 RL On-Line TOC Analyzer

Reliable, accurate performance for online TOC monitoring and real-time testing

Used extensively in the pharmaceutical industry, the Sievers 500 RL On-Line TOC Analyzer offers unmatched stability and performance. It provides online TOC analysis for compliance with USP <643> and other global pharmacopeia and can be provided with the critical protocols required for real-time testing (RTT) process validation. Specific features are offered for pharmaceutical applications, such as automated validation and system suitability testing, the ability to measure USP <645> conductivity, and compliance with 21 CFR Part 11. The 500 RL uses the most robust analytical technology available and is easy to implement and maintain.

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Features & Benefits

M500 Online Features & Benefits

Accuracy. Efficiency. Integrity.

  • 150% faster analysis time
  • Advanced communications: Ethernet, WiFi, 4-20mA, Modbus, and Serial connectivity
  • 10-inch color touchscreen
  • Super iOS 4-port sampler automates grad samples to improve productivity
  • Simultaneous TOC & conductivity measurement
  • Automated system suitability calibration, & validation
  • 50% faster validation protocols
  • IP55 & full IP connections
  • Same footprint as 500 RL for easy upgrades

Specifications

M500 Online Specifications

Total Organic Carbon
Linear Range 0.03 to 2,500 ppb as TOC
Accuracy ± 5% of measurement; ±0.1 ppb
Precision ± 1% of measurement; ±0.3 ppb
pH Range 5.5 to 8.0 in order to meet accuracy specification
Analysis Modes On-line, on-line averaged, on-line timed, Grab
Analysis Time1,2 3 minutes for continuous online measurements
Ozone Compatibility 50 ppb O3 continuous; 200 ppb 03 for 2 hours daily
External Flow Rate Minimum 50 mL/min
Sample Temperature 1–95 °C (34–203 °F) (withstands short-term exposure)
Sample Pressure Up to 100 psig
Interferences Insensitive to organic heteroatoms
Calibration Stability Typically stable for 12 months
Display Readout 3 significant digits

Conductivity
Raw Conductivity Range 0.01 to 800 µS/cm
Conductivity Accuracy 0.005 µS/cm or 1%, whichever is greater
Conductivity Precision <1.0% RSD

Instrument
Power Requirements 100–240 VAC, 70 W, 50/60 Hz
Fuses No user-replaceable fuses
Normal Operating Environment Intended for indoor use only
Ambient Temperature 5–40°C (41–104°F)
Maximum Relative Humidity Up to 95%, noncondensing
Maximum Altitude 3,000 m (9,843 ft)
Inputs Two isolated binary inputs
Outputs Serial (RS-232), one USB, three 40-20 mA, four alarms, one Ethernet
Installation/Overvoltage II (protects against transients present in Category II power)
Safety Certifications CE, ETL listed. Conforms to UL Std. 61010-1. Certified to CSA 22.2 No. 61010-1.
Pollution Degree 2 (normally only non-conductive pollution)
Display Backlit 10.1″, 1280×800, touchscreen display
Size H: 43.4 cm (17.1 in); W: 55.9 cm (22.0 in); D: 28.7 cm (11.3 in)
Weight 16.3 kg (36 lb)
IP Rating IP 55
Optional Wi-Fi 802.11ac/a/b/g/n Dual-band 2.4/5 GHz
Industrial Communications Protocol Modbus TCP/IP

 

1Time to first measurement is 10 minutes

2Base model analysis time is six minutes for continuous online measurement